3 February, 2012
Volume 10, Issue 2
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Volume 10, Issue 2
On the cover: This issue features a special review focus on hematopoietic stem cells (HSCs). The cover image is a watercolor painting by Linda Halcomb, Indianapolis, IN (USA) entitled “Blood Flow 2,” which is designed to depict blood and blood vessels. Linda completed this painting while her husband Ken was having hematopoietic cells harvested as part of his cancer treatment. Ken sadly lost his battle with cancer late last year, and the use of this image for our cover honors his life and his commitment to fighting his disease.
About the Cover
See here for some background behind the February (10,2) cover.
NEW!
Cell Stem Cell
Impact Factor:
25.943
Up from 23.563 last year!
© Thomson Reuters Journal Citation Reports (2011)
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Most Read Papers
These are the Top 20 papers by download from the Cell Stem Cell web site.
In the News
Read coverage of recent Cell Stem Cell articles in the popular press.
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Cell Stem Cell is the official affiliated journal of the International Society for Stem Cell Research (ISSCR).
ISSCR 2012: Submit your abstract now! Join the ISSCR in Yokohama, Japan, June 13-16, 2012. Cosponsored by the Japanese Science and Technology Agency (JST) and the Center for iPS Cell Research and Application (CiRA).More travel grants than ever are available; apply during the abstract submission process. Abstract and Travel Award Submission Deadline Extended to February 8.
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In This Issue
Explore the frontiers of HSC-based therapies, from creating an HIV-resistant immune system to producing red blood cells in vitro.
Review by Dick and colleagues.
CLINICAL PROGRESS
Engineering HSC Expansion, For the Clinic
A new clinically relevant culture system for producing HSCs enables an 11-fold increase in stem cells from cord blood.
Article by Zandstra and colleagues.
RESEARCH
Infection-Induced Hematopoiesis
Nitric oxide drives the proliferation of hematopoietic progenitors to produce more granulocytes in response to inflammatory stress.
RESEARCH
Nolan and colleagues help resolve conflicting data on CSCs, demonstrating that muliple cellular subsets clonally recapitulate AML.
RESEARCH
Fetal mammary SCs and their associated stroma exhibit gene expression programs related to those in breast cancer and BMP4 inhibits ERK via Smad-dependent regulation of DUSP9 in mouse ESCs to maintain self-renewal.
February Issue Featured Article
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ISSCR: Committee Forum
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One Year Ago...
Selected articles from January 2011:
CNV changes in human iPSCs during reprogramming (Resource by Loring and colleagues).
iPSC model of progeria reveals MSC defects (Colman and colleagues).
EGFR/Ras/MAPK signaling plays an essential role in maintenance of intestinal stem cells (Edgar and colleagues).
Review on DNA damage and drug resistance in cancer stem cells.
(Blanpain, Passegué and colleagues).
All Cell Stem Cell articles from a year ago or more are available online for free.
Stem Cell Articles in Other Cell Press Journals
A Subpopulation of Adult Skeletal Muscle Stem Cells Retains All Template DNA Strands after Cell Division
Pierre Rocheteau, Barbara Gayraud-Morel, Irene Siegl-Cachedenier, Maria A. Blasco, Shahragim Tajbakhsh
Summary | Full Text | PDF
20 January 2012 Cell
Generation of Chimeric Rhesus Monkeys
Masahito Tachibana, Michelle Sparman, Cathy Ramsey, Hong Ma, Hyo-Sang Lee, Maria Cecilia T. Penedo, Shoukhrat Mitalipov
Summary | Full Text | PDF
20 January 2012 Cell
Self-Renewal Does Not Predict Tumor Growth Potential in Mouse Models of High-Grade Glioma
Lindy E. Barrett, Zvi Granot, Courtney Coker, Antonio Iavarone, Dolores Hambardzumyan, Eric C. Holland, Hyung-song Nam, Robert Benezra
Summary | Full Text | PDF
217 January 2012 Cancer Cell
Canonical Wnt Signaling Dynamically Controls Multiple Stem Cell Fate Decisions during Vertebrate Body Formation
Benjamin L. Martin, David Kimelman
Summary | Full Text | PDF
17 January 2012 Developmental Cell
Bile Acid and Inflammation Activate Gastric Cardia Stem Cells in a Mouse Model of Barrett-Like Metaplasia
Michael Quante, Govind Bhagat, Julian A. Abrams, Frederic Marache, Pamela Good, Michele D. Lee, Yoomi Lee, Richard Friedman, Samuel Asfaha, Zinaida Dubeykovskaya et al.
Summary | Full Text | PDF
17 January 2012 Cancer Cell
Tre1 GPCR Signaling Orients Stem Cell Divisions in the Drosophila Central Nervous System
Shigeki Yoshiura, Nao Ohta, Fumio Matsuzaki
Summary | Full Text | PDF
17 January 2012 Developmental Cell
Somatic Progenitor Cell Vulnerability to Mitochondrial DNA Mutagenesis Underlies Progeroid Phenotypes in Polg Mutator Mice
Kati J. Ahlqvist, Riikka H. Hämäläinen, Shuichi Yatsuga, Marko Uutela, Mügen Terzioglu, Alexandra Götz, Saara Forsström, Petri Salven, Alexandre Angers-Loustau, Outi H. Kopra et al.
Summary | Full Text | PDF
4 January 2012 Cell Metabolism
